Agricola Family Edition, simple rules and a strong theme make this game easily accessable to everybody: Build your own farm! you need room for yourself and your family, feilds for farming, and pastures for a lot of animals.
Send out your people to work! In order to take an action in Agricola, you need place a person on an action space. This will provide you with the grain, allow you to plow fields and you can even build a wind mill - just like that!
Diversity is key! Monoculture is boring. Keep a good balance between farming and animal husbandry and you will have a flourishing and nice looking farm in the end, whether you win or not.